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Mometasone Nasal
Nasonex

  • Elocom / Eziwin / Propel / Sinuva
  • ALL008
  • In Stock

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   Manufacturer's Suggested Retail Price (MSRP) per bottle is $66.86 ! Buying from us will save you at least 41.18%

Package per bottle Price SAVINGS BONUS Order
50mcg * 3 bottles
$39.33 $117.99 $0.00
+ SILVER BONUS
SILVER BONUS
for orders under $300
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►Next orders 10% discount
50mcg * 6 bottles
$24.66 $147.96 $88.02
+ SILVER BONUS
SILVER BONUS
for orders under $300
►Package delivery insurance
►Next orders 10% discount
50mcg * 9 bottles
$19.99 $179.91 $174.06
+ SILVER BONUS
SILVER BONUS
for orders under $300
►Package delivery insurance
►Next orders 10% discount
50mcg * 12 bottles
$17.99 $215.88 $256.08
+ SILVER BONUS
SILVER BONUS
for orders under $300
►Package delivery insurance
►Next orders 10% discount

Mometasone is a medium-potency synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties. Studies in asthmatic patients have demonstrated that mometasone provides a favorable ratio of topical to systemic activity due to its primary local effect along with the extensive hepatic metabolism and the lack of active metabolites.

Maximum improvement in symptoms following inhaled administration of mometasone furoate may not be achieved for 1 to 2 weeks or longer after starting treatment. The anti-inflammatory actions of corticosteroids are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.

Mometasone nasal (for use in the nose) is used to treat nasal symptoms of seasonal or year-round allergies, including congestion, sneezing, and runny nose. Mometasone nasal is approved for this use in adults and children who are at least 2 years old.

Mometasone nasal is also used to prevent seasonal allergy symptoms in adults and children who are at least 12 years old.
Mometasone nasal is used to treat nasal polyps only in adults.

Mometasone is a medium-potency synthetic corticosteroid with antiinflammatory, antipruritic, and vasoconstrictive properties. Studies in asthmatic patients have demonstrated that mometasone provides a favorable ratio of topical to systemic activity due to its primary local effect along with the extensive hepatic metabolism and the lack of active metabolites. Though effective for the treatment of asthma, glucocorticoids do not affect asthma symptoms immediately.

Maximum improvement in symptoms following inhaled administration of mometasone furoate may not be achieved for 1 to 2 weeks or longer after starting treatment. When glucocorticoids are discontinued, asthma stability may persist for several days or longer.

Mometasone has been shown in vitro to exhibit a binding affinity for the human glucocorticoid receptor which is approximately 12 times that of dexamethasone, 7 times that of triamcinolone acetonide, 5 times that of budesonide, and 1.5 times that of fluticasone. The clinical significance of these findings is unknown.

Unbound corticosteroids cross cell membranes and bind with high affinity to specific cytoplasmic receptors. Inflammation is decreased by diminishing the release of leukocytic acid hydrolases, prevention of macrophage accumulation at inflamed sites, interference with leukocyte adhesion to the capillary wall, reduction of capillary membrane permeability, reduction of complement components, inhibition of histamine and kinin release, and interference with the formation of scar tissue.

The antiinflammatory actions of corticosteroids are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.

Mometasone furoate has been shown in vitro to exhibit a binding affinity for the human glucocorticoid receptor which is approximately 12 times that of dexamethasone, 7 times that of triamcinolone acetonide, 5 times that of budesonide, and 1.5 times that of fluticasone.

Metabolism: Hepatic. Extensive metabolism to multiple metabolites. There are no major metabolites detectable in plasma. Upon in vitro incubation, one of the minor metabolites formed is 6ß-hydroxy-mometasone furoate. In human liver microsomes, the formation of the metabolite is regulated by cytochrome P-450 3A4.

Absorption: Nasal spray is virtually undetectable in plasma

Route of elimination: N/A

Half life: 5.8 hours

All medicines may cause side effects, but many people have no, or minor, side effects.Some medical conditions may interact with Mometasone.

Tell your doctor or pharmacist if you have any medical conditions.

Common side effects may include: nosebleeds, headache, stuffy nose, sore throat, cough or flu-like symptoms.

The potential for acute toxic effects following overdose with the mometasone inhaler is low. However, habitual overuse of the product can cause symptoms of steroid overload, including menstrual irregularities, acne, obesity, and muscle weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

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