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Roxithromycin
Rulid

  • Claramid / Renicin / Roxy-150 / Surlid
  • ANT026
  • In Stock

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Package per pill Price SAVINGS BONUS Order
150mg * 30 pills
$3.36 $100.80 $0.00
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150mg * 60 pills
$1.96 $117.60 $84.00
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150mg * 90 pills
$1.46 $131.40 $171.00
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150mg * 120 pills
$1.19 $142.80 $260.40
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150mg * 180 pills
$0.96 $172.80 $432.00
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Roxithromycin is a semi-synthetic macrolide antibiotic. It is very similar in composition, chemical structure and mechanism of action to erythromycin, azithromycin, or clarithromycin.

Roxithromycin prevents bacteria from growing, by interfering with their protein synthesis. Roxithromycin binds to the subunit 50S of the bacterial ribosome, and thus inhibits the translocation of peptides.

Roxithromycin has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila. It can treat respiratory tract, urinary and soft tissue infections. It is not available in the United States, but is available in Australia.

Used to treat respiratory tract, urinary and soft tissue infections.

Roxithromycin is a semi-synthetic macrolide antibiotic. It is very similar in composition, chemical structure and mechanism of action to erythromycin, azithromycin, or clarithromycin.

Roxithromycin has the following antibacterial spectrum in vitro: Streptococcus agalactiae, Streptococcus pneumoniae (Pneumococcus), Neisseria meningitides (Meningococcus), Listeria monocytogenes, Mycoplasma pneumoniae, Chlamydia trachomatis, Ureaplasma urealyticum, Legionella pneumophila, Helicobacter (Campylobacter), Gardnerella vaginalis, Bordetella pertussis, Moraxella catarrhalis (Branhamella Catarrhalis), and Haemophilus ducreyi.

Roxithromycin is highly concentrated in polymorphonuclear leukocytes and macrophages, achieving intracellular concentrations greater than those outside the cell. Roxithromycin enhances the adhesive and chemotactic functions of these cells which in the presence of infection produce phagocytosis and bacterial lysis. Roxithromycin also possesses intracellular bactericidal activity.

Roxithromycin prevents bacteria from growing, by interfering with their protein synthesis.

Roxithromycin binds to the subunit 50S of the bacterial ribosome, and thus inhibits the translocation of peptides. Roxithromycin has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila.

Metabolism: Hepatic. Roxithromycin is only partially metabolised, more than half the parent compound being excreted unchanged. Three metabolites have been identified in urine and faeces: the major metabolite is descladinose roxithromycin, with N-mono and N-di-demethyl roxithromycin as minor metabolites. The respective percentage of roxithromycin and these three metabolites is similar in urine and faeces.

Absorption: Very rapidly absorbed and diffused into most tissues and phagocytes.

Route of elimination: N/A

Half life: 12 hours

Affected organisms: Enteric bacteria and other eubacteria.

All medicines may cause side effects, but many people have no, or minor, side effects.Some medical conditions may interact with Roxithromycin.

Tell your doctor or pharmacist if you have any medical conditions.

Most common side-effects are gastrointestinal; diarrhoea, nausea, abdominal pain and vomiting.
Less common side-effects include headaches, rashes, abnormal liver function values and alteration in senses of smell and taste.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

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